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Image Search Results
Journal: Scientific Reports
Article Title: All-optical Reflection-mode Microscopic Histology of Unstained Human Tissues
doi: 10.1038/s41598-019-49849-9
Figure Lengend Snippet: A comparison between a PARS images and ( a ) a bright field image at the of the same breast tissue sample with invasive ductal carcinoma. ( b ) an unstained slide imaged with a conventional bright field microscope. A PARS acquisition of the regions is shown for the unstained tissue slide with ( c ) a false H&E colour map applied and a ( d ) logarithmic greyscale colour map applied. A PARS acquisition of a FFPE block with ( e ) a false H&E colour map applied and ( f ) a logarithmic greyscale colour map applied. Green outline highlights a sharp delineation between a hypercellular region of tissue and healthy tissue, blue outline represents a high-grade malignancy with serosity and necrotic cells, the red outline represents an artifact present in the slides. Scale bar 100 µm.
Article Snippet: The unstained samples are imaged using the PARS apparatus detailed in Fig. whereas the H&E images are acquired using a standard
Techniques: Comparison, Microscopy, Blocking Assay
Journal: Scientific Reports
Article Title: All-optical Reflection-mode Microscopic Histology of Unstained Human Tissues
doi: 10.1038/s41598-019-49849-9
Figure Lengend Snippet: ( a ) A standard H&E prepared slide imaged with a standard pathology microscope of a blood vessel (within green outline) located in pancreatic tissue, surrounded by muscular layer (between green and yellow outline) with smooth muscle cells. ( b ) An unstained tissue slide of the adjacent section imaged with PARS. ( c ) A direct overlay of the images ( a , b ). Scale bar 100 µm.
Article Snippet: The unstained samples are imaged using the PARS apparatus detailed in Fig. whereas the H&E images are acquired using a standard
Techniques: Microscopy
Journal: Scientific Reports
Article Title: All-optical Reflection-mode Microscopic Histology of Unstained Human Tissues
doi: 10.1038/s41598-019-49849-9
Figure Lengend Snippet: Quantitative study from ( a ) an image of a standard H&E prepared breast tissue sample captured by a commercial bright field microscope ( b ) a PARS image of the adjacent breast tissue section on the FFPE block. ( c ) A comparison of the cross-sectional nuclear area, ( d ) a comparison of the internuclear distance between cell nuclei, and ( e ) a comparison of the circularity ratio extracted from images ( a , b ). See Table for further details.
Article Snippet: The unstained samples are imaged using the PARS apparatus detailed in Fig. whereas the H&E images are acquired using a standard
Techniques: Microscopy, Blocking Assay, Comparison